The E. coli β-lactamase attenuator mediates growth rate-dependent regulation
Authors:
- BengtBEBengt
- [Aring][A[Aring]
- Ke JaurinKJKe Jaurin
- Thomas GrundströmTGThomas Grundström
- Thomas EdlundTEThomas Edlund
- Staffan NormarkSNStaffan Normark
- 1 March 1981
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 290 (5803) , 221-225
Abstract
We have identified a new control or attenuator region in the chromosomal beta-lactamase operon of Escherichia coli. A single base alteration within its attenuator led to a loss in the cell's ability to coordinate its content of beta-lactamase with growth rate. We suggest a mechanism through which this mode of regulation operates.Keywords
This publication has 28 references indexed in Scilit:
- E. coli RNA polymerase interacts homologously with two different promotersCell, 1980
- Linkage map of Escherichia coli K-12, edition 6Microbiological Reviews, 1980
- Secretion and Membrane Localization of Proteins inEscherichia ColiCritical Reviews in Biochemistry, 1980
- REGULATORY SEQUENCES INVOLVED IN THE PROMOTION AND TERMINATION OF RNA TRANSCRIPTIONAnnual Review of Genetics, 1979
- Direct chemical method for sequencing RNA.Proceedings of the National Academy of Sciences, 1979
- Genetic Control Signals in DNA1979
- Regulation of the Protein-Synthesizing Machinery—Ribosomes, tRNA, Factors, and So On1979
- Isolation and characterization of DNA repetitions carrying the chromosomal β-lactamase gene of Escherichia coli K-12Molecular Genetics and Genomics, 1979
- Patterns of protein synthesis in E. coli: a catalog of the amount of 140 individual proteins at different growth ratesCell, 1978
- Improved Estimation of Secondary Structure in Ribonucleic AcidsNature New Biology, 1973