Ptychographic lensless coherent endomicroscopy through a flexible fiber bundle
Authors:
- Wonshik ChoiWCWonshik Choi
- Ori KatzOKOri Katz
Preprint
Abstract
Conventional fiber-bundle-based endoscopes allow minimally invasive imaging through flexible multi-core fiber (MCF) bundles by placing a miniature lens at the distal tip and using each core as an imaging pixel. In recent years, lensless imaging through MCFs was made possible by correcting the core-to-core phase distortions pre-measured in a calibration procedure. However, temporally varying wavefront distortions, for instance, due to dynamic fiber bending, pose a challenge for such approaches. Here, we demonstrate a coherent lensless imaging technique based on intensity-only measurements insensitive to core-to-core phase distortions. We leverage a ptychographic reconstruction algorithm to retrieve the phase and amplitude profiles of reflective objects placed at a distance from the fiber tip, using as input a set of diffracted intensity patterns reflected from the object when the illumination is scanned over the MCF cores. Our approach thus utilizes an acquisition process equivalent to confocal microendoscopy, only replacing the single detector with a camera.Keywords
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This publication has 44 references indexed in Scilit:
- A flexible two-photon fiberscope for fast activity imaging and precise optogenetic photostimulation of neurons in freely moving miceNeuron, 2022
- Flexible-type ultrathin holographic endoscope for microscopic imaging of unstained biological tissuesNature Communications, 2022
- Wavelength-multiplexed single-shot ptychographyUltramicroscopy, 2022
- Memory effect assisted imaging through multimode optical fibresNature Communications, 2021
- Seeing through chaos in multimode fibresNature Photonics, 2015
- Optical fibers for high-resolution in vivo microendoscopic fluorescence imagingOptical Fiber Technology, 2013
- Exploiting multimode waveguides for pure fibre-based imagingNature Communications, 2012
- Probe retrieval in ptychographic coherent diffractive imagingUltramicroscopy, 2009
- Endoscope-compatible confocal microscope using a gradient index-lens systemOptics Communications, 2001
- Loss Analysis of Single-Mode Fiber SplicesBell System Technical Journal, 1977