Mathematical model of the amoeba-inspired combinatorial optimization machine for physical implementation and its equivalence to recurrent neural networks
Open Access
- 9 June 2026
- journal article
- Published by American Physical Society (APS) in Physical Review Research
- Vol. 8 (2)
Abstract
Information-processing algorithms inspired by survival strategies of slime molds have been intensively studied to realize combinatorial optimization machines with high computational efficiency and low power consumption. However, previously proposed mathematical models are not suitable for physical implementation as they involved constraints due to the volume-conservation law of slime molds, multiple conditional branches, and numerous complex functions such as sigmoid functions. Here, we propose a mathematical model, the Amoeba TSP (traveling salesman problem) recurrence formula model, which simplifies the information-processing procedure and enables physical implementation without sacrificing optimization performance. Specifically, we demonstrate using numerical simulations that (1) the conservation-law constraints assumed in previous models can be removed, (2) several sigmoid functions can be eliminated, and (3) Gaussian-distribution random numbers that can be generated from thermal fluctuations can be employed as random fluctuations. These improvements broaden the range of candidate materials and phenomena for physical implementation and reduce the number of device components required. Furthermore, we discover that our mathematical model integrating these modifications is mathematically equivalent to a recurrent neural network with fixed weights that exploits nonlinear dynamics. Remarkably, despite its significant simplification, the proposed model exhibits superior solution-search performance compared with the previous models in terms of solution quality, convergence speed, and scalability. Our results open a practical pathway toward realization of highly efficient and high-performance combinatorial optimization machines based on non-von Neumann-type architectures and provide insights into bioinspired information processing by uncovering a connection between the computational principles of slime molds and recurrent neural networks.Keywords
Funding Information
- Waseda University (2023E-026)
- Waseda University (2024C-155)
- Waseda University (2025C-491)
- Waseda University (2023C-140)
- Waseda University (2024C-153)
- Waseda University (2025C-133)
- Japan Society for the Promotion of Science (JP24H02231)
- Japan Society for the Promotion of Science (JP25H00611)
- Japan Science and Technology Agency (JPMJCR20T1)
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