Lower Genital Tract Infections Among HIV-Infected and High-Risk Uninfected Women

Authors:
  • PBPeter Bacchetti
    Peter Bacchetti
  • SBSusan Barkan
    Susan Barkan
  • MAMichael Augenbraun
    Michael Augenbraun
  • SSSylvia Silver
    Sylvia Silver
  • RDRobert Delapenha
    Robert Delapenha
  • PGPatricia Garcia
    Patricia Garcia
  • UMUsha Mathur
    Usha Mathur
  • PMPaolo Miotti
    Paolo Miotti
  • DBDavid Burns
    David Burns
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Abstract
Background and Objectives: Few comparisons of factors associated with sexually transmitted diseases (STDs) and HIV are available for representative samples of American women. Goal of the Study: To compare factors associated with STDs in a large sample of women infected with HIV and women not infected with HIV. Study Design: A cross-sectional analysis of STDs in 2,058 women seropositive (HIV+) for HIV and 567 women seronegative (HIV−) for HIV. Results: HIV+ women were more likely than HIV− women to report previous STDs, with the exceptions of chlamydia and bacterial vaginosis. Both HIV status and CD4 lymphocyte count were associated with evidence of genital ulcerations, warts, and vaginal candidiasis (p Conclusions: In this North American cohort, HIV+ women were more likely than HIV− women to report previous genital tract infections and symptoms. However, the HIV+ women reported less recent sexual activity and few gonococcal or chlamydial infections.

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