Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model
Open Access
- 24 November 2016
- journal article
- Published by Ferrata Storti Foundation (Haematologica) in Haematologica
- Vol. 102 (3) , e85-e88
Abstract
Anemia is very common in chronic kidney disease (CKD) patients,[1][1] and has been associated with adverse cardiovascular outcomes in this population.[2][2] The pathogenesis of CKD-associated anemia is multifactorial, contributed to by relative erythropoietin (Epo) deficiency, absolute andKeywords
This publication has 15 references indexed in Scilit:
- Lack of hepcidin ameliorates anemia and improves growth in an adenine-induced mouse model of chronic kidney diseaseAmerican Journal of Physiology-Renal Physiology, 2016
- Hepcidin-25 Concentrations Are Markedly Increased in Patients With Chronic Kidney Disease and Are Inversely Correlated With Estimated Glomerular Filtration RatesJournal of Clinical Laboratory Analysis, 2013
- Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with ageHaematologica, 2013
- A novel model of adenine-induced tubulointerstitial nephropathy in miceBMC Nephrology, 2013
- Current Status of the Measurement of Blood Hepcidin Levels in Chronic Kidney DiseaseClinical Journal of the American Society of Nephrology, 2010
- Hepcidin—A Potential Novel Biomarker for Iron Status in Chronic Kidney DiseaseClinical Journal of the American Society of Nephrology, 2009
- Immunoassay for human serum hepcidinBlood, 2008
- Secondary analysis of the CHOIR trial epoetin-α dose and achieved hemoglobin outcomesKidney International, 2008
- Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammationBlood, 2007
- Association of High Serum Creatinine and Anemia Increases the Risk of Coronary EventsJournal of the American Society of Nephrology, 2003