Multicomponent Reaction: Palladium-Catalyzed Carbonylation of Aryl Halides and Alkyl Halides to Aromatic Esters
- 14 September 2022
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 88 (8) , 5153-5160
Abstract
A convenient four-component reaction has been developed that allows for the direct transformation of aryl iodides with alkyl halides into the corresponding aromatic esters and diesters via palladium-catalyzed carbonylation with water as solvent. Various esters and diesters were isolated in moderate to good yields with broad functional group tolerance.Keywords
Funding Information
- National Natural Science Foundation of China (21901148)
- Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi
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