Biased Agonism/Antagonism of Cardiovascular GPCRs for Heart Failure Therapy

This publication has 89 references indexed in Scilit:

• Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol
  Structure, 2012
• Alpha-1-adrenergic receptors: Targets for agonist drugs to treat heart failure
  Journal of Molecular and Cellular Cardiology, 2011
• SUMO1-dependent modulation of SERCA2a in heart failure
  Nature, 2011
• Therapeutic potential of β-arrestin- and G protein-biased agonists
  Trends in Molecular Medicine, 2011
• Adrenal Beta-Arrestin 1 Inhibition In Vivo Attenuates Post-Myocardial Infarction Progression to Heart Failure and Adverse Remodeling Via Reduction of Circulating Aldosterone Levels
  JACC, 2011
• Physiological and pharmacological implications of beta-arrestin regulation
  Pharmacology & Therapeutics, 2009
• β-Blockers alprenolol and carvedilol stimulate β-arrestin-mediated EGFR transactivation
  Proceedings of the National Academy of Sciences, 2008
• Carvedilol increases blood pressure response to phenylephrine infusion in heart failure subjects with systolic dysfunction: Evidence of improved vascular α1-adrenoreceptor signal transduction
  American Heart Journal, 2008
• Apelin increases contractility in failing cardiac muscle
  European Journal of Pharmacology, 2006
• β-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
  Proceedings of the National Academy of Sciences, 2006