Continuous Flow Synthesis of Metal–NHC Complexes**

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Abstract
The use of weak bases and mild conditions is currently the most sustainable and attractive synthetic approach for the preparation of late‐transition metal complexes, some of which are widely used in catalysis, medicinal chemistry and materials science. Herein, the use of cuprate, aurate or palladate species for a continuous flow preparation of CuI, AuI and PdII‐NHC complexes is reported. All reactions examined proceed under extremely mild conditions and make use of technical grade acetone as solvent. The scalability of the process was exemplified in a multigram‐scale synthesis of [Cu(IPr)Cl].
Funding Information
  • Bijzonder Onderzoeksfonds UGent

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