Figure S8 from Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1

Authors:

HKHiroki Kobayashi
Hiroki Kobayashi
YOYosuke Ochiai
Yosuke Ochiai
Junya Arai
Junya Arai
MHMasahiro Hata
Masahiro Hata
FWFeijing Wu
Feijing Wu
MSMasaki Sunagawa
Masaki Sunagawa
TITadashi Iida
Tadashi Iida
TBTaisuke Baba
Taisuke Baba
EMErmanno Malagola
Ermanno Malagola
TTTakayuki Tanaka
Takayuki Tanaka
ZJZhengyu Jiang
Zhengyu Jiang
RWRuth A. White
Ruth A. White

Open Access

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17 June 2026

other
Published by American Association for Cancer Research (AACR)

DOI:10.1158/0008-5472.32710066

Abstract

Figure S8 shows that innervation is increased in PDAC liver metastasis and that NTN1 overexpression in Panc02 cells promotes the growth of PDAC liver metastasis in a splenic injection model.

Keywords

GASTROINTESTINAL CANCERS
PANCREATIC CANCER
PROGRESSION, INVASION & METASTASIS
METASTASIS
TUMOR MICROENVIRONMENT