SRC2-3 binds to vitamin D receptor with high sensitivity and strong affinity
- 1 January 2017
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 25 (2) , 568-574
Abstract
No abstract availableKeywords
Funding Information
- Japan Agency for Medical Research and Development
- Ministry of Education, Culture, Sports, Science, and Technology (26460155)
This publication has 19 references indexed in Scilit:
- Relationship between Structure and Conformational Change of the Vitamin D Receptor Ligand Binding Domain in 1α,25-Dihydroxyvitamin D3 SignalingMolecules, 2015
- Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activityBioorganic & Medicinal Chemistry, 2015
- Structural considerations of vitamin D signalingFrontiers in Physiology, 2014
- Regulation of target gene expression by the vitamin D receptor - an update on mechanismsReviews in Endocrine and Metabolic Disorders, 2011
- Pharmaceutical Studies on Vitamin D Derivatives and Practical Syntheses of Six Commercially Available Vitamin D Derivatives That Contribute to Current Clinical PracticeHETEROCYCLES, 2010
- A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the ReceptorJournal of Medicinal Chemistry, 2009
- 2-Substituted-16-ene-22-thia-1α,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structureBioorganic & Medicinal Chemistry, 2008
- Ligand-mediated conformational changes of the VDR are required for gene transactivationThe Journal of Steroid Biochemistry and Molecular Biology, 2004
- Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D3 Hormone Analogues and a LXXLL-Containing Coactivator Peptide,Biochemistry, 2004
- Structure and specificity of nuclear receptor–coactivator interactionsGenes & Development, 1998