Discriminating acidic and alkaline enzymes using a random forest model with secondary structure amino acid composition
Authors:
- Guangya ZhangGZGuangya Zhang
- Hongchun LiHLHongchun Li
- Baishan FangBFBaishan Fang
- 1 June 2009
- journal article
- Published by Elsevier in Process Biochemistry
- Vol. 44 (6) , 654-660
Abstract
No abstract availableKeywords
This publication has 79 references indexed in Scilit:
- Life in acid: pH homeostasis in acidophilesTrends in Microbiology, 2007
- Structural and Mechanistic Exploration of Acid Resistance: Kinetic Stability Facilitates Evolution of Extremophilic BehaviorJournal of Molecular Biology, 2007
- Prediction of protein stability changes for single‐site mutations using support vector machinesProteins: Structure, Function, and Bioinformatics, 2005
- Enzyme adaptation to alkaline pH: Atomic resolution (1.08 Å) structure of phosphoserine aminotransferase from Bacillus alcalophilusProtein Science, 2005
- Acidophilic adaptations in the structure ofAcetobacter aceti N5-carboxyaminoimidazole ribonucleotide mutase (PurE)Acta Crystallographica Section D Structural Biology, 2004
- Analysis of the genome of an alkaliphilic Bacillus strain from an industrial point of viewExtremophiles, 2000
- ExtremozymesCurrent Opinion in Chemical Biology, 1999
- The stability of proteins in extreme environmentsCurrent Opinion in Structural Biology, 1998
- Protonation Behavior of Histidine 24 and Histidine 119 in Forming the pH 4 Folding Intermediate of ApomyoglobinBiochemistry, 1998
- High-resolution crystal structure of M-protease: phylogeny aided analysis of the high-alkaline adaptation mechanismProtein Engineering, Design and Selection, 1997