Oral amoxycillin, an alternative treatment for neurosyphilis.
Authors:
- R E MorrisonRMR E Morrison
- S M HarrisonSHS M Harrison
- E C TramontETE C Tramont
- 1 December 1985
- journal article
- research article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 61 (6) , 359-362
Abstract
A serum amoxycillin concentration of 0.11 g/l was established as being treponemicidal in a rabbit model with orchitis. Seventeen patients treated with amoxycillin 2 g by mouth three times a day plus 500 mg probenecid twice a day attained treponemicidal CSF amoxycillin concentrations. Thus amoxycillin by mouth offers an effective alternative method for treating patients with neurosyphilis.Keywords
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