Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome
Authors:
- 31 October 2024
- journal article
- research article
- Published by Elsevier in Molecular Cell
- Vol. 84 (21) , 4059-4078.e10
Abstract
No abstract availableKeywords
Funding Information
- National Cancer Institute
- Minnesota Supercomputing Institute, University of Minnesota
- National Institutes of Health (R01 GM149666)
This publication has 103 references indexed in Scilit:
- Characterization of p53/p63/p73 and Myc expressions during embryogenesis of the sea urchinDevelopmental Dynamics, 2023
- MYC-induced metabolic stress and tumorigenesisBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2018
- p63 involvement in poly(ADP-ribose) polymerase 1 signaling of topoisomerase I-dependent DNA damage in carcinoma cellsBiochemical Pharmacology, 2013
- MYC on the Path to CancerCell, 2012
- Hallmarks of Cancer: The Next GenerationCell, 2011
- DNA damage response to the Mdm2 inhibitor Nutlin-3Biochemical Pharmacology, 2010
- Human Topoisomerase IIα and IIβ Interact with the C-Terminal Region of p53Experimental Cell Research, 2000
- The role of p53 in tumour suppression: lessons from mouse modelsCellular and Molecular Life Sciences, 1999
- Induction of apoptosis in fibroblasts by c-myc proteinCell, 1992
- Transcription generates positively and negatively supercoiled domains in the templateCell, 1988