Estrogen Activation of G-Protein–Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes
- 1 May 2019
- journal article
- research article
- Published by Elsevier in Gastroenterology
- Vol. 156 (6) , 1788-1804.e13
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (R01DK090311, R01DK056626, R01DK105198, R01 DK103046, R24OD017870, 5K08CA172288, R37DK048873)
This publication has 54 references indexed in Scilit:
- A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissueNature Protocols, 2012
- mTOR Signaling in Growth Control and DiseaseCell, 2012
- Haploinsufficiency of Target of Rapamycin Attenuates Cardiomyopathies in Adult ZebrafishCirculation Research, 2011
- Targeted gene disruption in somatic zebrafish cells using engineered TALENsNature Biotechnology, 2011
- PGE2-regulated wnt signaling andN-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injuryProceedings of the National Academy of Sciences, 2010
- Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female ratsAmerican Journal of Physiology-Heart and Circulatory Physiology, 2009
- Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and RegenerationCell, 2009
- Pivotal Role of mTOR Signaling in Hepatocellular CarcinomaGastroenterology, 2008
- APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver developmentDevelopmental Biology, 2008
- AKT/PKB Signaling: Navigating DownstreamCell, 2007