Breaking the computational barrier: a divide-conquer and aggregate based approach for Alu insertion site characterisation
- 1 January 2009
- journal article
- Published by Inderscience Publishers in International Journal of Computational Biology and Drug Design
- Vol. 2 (4) , 302-22
Abstract
Insertion site characterisation of Alu elements is an important problem in primate-specific bioinformatics research. Key characteristics of this challenging problem include: data are not in the pre-defined feature vectors for predictive model construction; without any prior knowledge, can we discover the general patterns that could exist and also make biological insights?; how to obtain the compact yet discriminative patterns given a search space of 4Keywords
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