Patterns of muscular strain in the embryonic heart wall

Authors:
  • BDBrooke J. Damon
    Brooke J. Damon
  • MRMathieu Rémond
    Mathieu Rémond
  • MBMichael R. Bigelow
    Michael R. Bigelow
  • TTThomas C. Trusk
    Thomas C. Trusk
  • SDStewart Denslow
    Stewart Denslow
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Abstract
HH Stage 22 chick heart inflated ex ovo with perfusate containing propidium iodide (red) and 3000 MW dextran (green), viewed here in left sagittal plane by confocal microscopy of acrylamide slab sections. Stretch‐sensitive membrane leaks were conspicuous along subendocardial trabeculae near the apex of the looped ventricle (bottom) and along inner wall of AV canal (inset), indicating peak strain of inner wall myocytes as modeled and measured by Damon et al., Developmental Dynamics 238:1535–1546.