Population-Based Applications and Analytics Using Patient-Reported Outcome Measures

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Abstract
The intersection of big data and artificial intelligence (AI) has resulted in advances in numerous areas, including machine learning, computer vision, and natural language processing. Although there are many potentially transformative applications of AI in health care, including precision medicine, this industry has been slow to adopt these technologies. At the same time, the operations of health care have historically been system-directed and physician-directed rather than patient-centered. The application of AI to patient-reported outcome measures (PROMs), which provide insight into patient-centered health outcomes, could steer research and healthcare delivery toward decisions that optimize outcomes important to patients. Historically, PROMs have only been collected within research registries. However, the increasing availability of PROMs within electronic health records has led to their inclusion in big data ecosystems, where they can inform or be informed by other data elements. The use of big data to analyze PROMs can help establish norms, evaluate data distribution, and determine proportions of patients achieving change or threshold standards. This information can be used for benchmarking, risk adjustment, predictive modeling, and ultimately improving the health of individuals and populations.

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