Quantifying Healthcare Provider Perceptions of a Novel Deep Learning Algorithm to Predict Sepsis: Electronic Survey
Authors:
- Karthik Bs RameshKRKarthik Bs Ramesh
- Aaron BoussinaABAaron Boussina
- Supreeth P. ShashikumarSSSupreeth P. Shashikumar
- Atul MalhotraAMAtul Malhotra
- Christopher A. LonghurstCLChristopher A. Longhurst
- Christopher S. JosefCJChristopher S. Josef
- Kimberly Rn QuinteroKQKimberly Rn Quintero
- Jake Del RossoJRJake Del Rosso
- Shamim NematiSNShamim Nemati
- Gabriel WardiGWGabriel Wardi
Open Access
- 4 June 2025
- journal article
- qualitative and-mixed-methods-study
- Published by Wolters Kluwer Health in Critical Care Explorations
- Vol. 7 (6) , e1276
Abstract
IMPORTANCE: Sepsis is a major cause of morbidity and mortality, with early intervention shown to improve outcomes. Predictive modeling and artificial intelligence (AI) can aid in early sepsis recognition, but there remains a gap between algorithm development and clinical use. Despite the importance of user experience in adopting clinical predictive models, few studies have focused on provider acceptance and feedback. OBJECTIVES: To evaluate healthcare worker perception and acceptance of a deep learning sepsis prediction model in the emergency department (ED). DESIGN, SETTING, AND PARTICIPANTS: COnformal Multidimensional Prediction Of SEpsis Risk (COMPOSER), a deep learning algorithm, is used at two EDs of a large academic medical center to predict sepsis before clear clinical presentation. An internally developed survey following the Checklist for Reporting Results of Internet E-Surveys was distributed to team members who received a COMPOSER alert. ANALYSIS: Mann-Whitney U testing was performed on results stratified by provider experience. RESULTS: A total of 114 responses were received: 76 from doctors of medicine/doctors of osteopathic medicine, 34 from registered nurses, and four from nurse practicioners/physician assistants. Of these, 53% were from providers with fewer than 5 years of experience. Seventy-seven percent of respondents had a positive or neutral perception of the alert’s usefulness. Providers with 0–5 years of experience were more likely to expect sepsis after the alert (p = 0.021) and found the alert more useful (p = 0.016) compared with those with 6+ years of experience. Additionally, physicians with 0–5 years of experience were more likely to say the alert changed their patient management (p = 0.048). CONCLUSIONS: Less experienced providers were more likely to perceive benefit from the alert, which was overall received favorably. Future AI implementations might consider tailored alert patterns and education to enhance reception and reduce fatigue.Keywords
This publication has 30 references indexed in Scilit:
- Factors driving provider adoption of the TREWS machine learning-based early warning system and its effects on sepsis treatment timingNature Medicine, 2022
- Prospective, multi-site study of patient outcomes after implementation of the TREWS machine learning-based early warning system for sepsisNature Medicine, 2022
- External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized PatientsJAMA Internal Medicine, 2021
- DeepAISE – An interpretable and recurrent neural survival model for early prediction of sepsisArtificial Intelligence in Medicine, 2021
- Association of a Care Bundle for Early Sepsis Management With Mortality Among Patients With Hospital-Onset or Community-Onset SepsisJAMA Internal Medicine, 2020
- Concurrence of big data analytics and healthcare: A systematic reviewInternational Journal of Medical Informatics, 2018
- Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014JAMA, 2017
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)JAMA, 2016
- Assessment of Clinical Criteria for SepsisJAMA, 2016
- The Surviving Sepsis Campaign bundles and outcome: results from the International Multicentre Prevalence Study on Sepsis (the IMPreSS study)Intensive Care Medicine, 2015