Regulation of endocytic traffic by Rho GTPases
Authors:
- 15 April 2003
- journal article
- review article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 371 (2) , 233-241
Abstract
The members of the Rho subfamily of small GTPases are key regulators of the actin cytoskeleton. However, recent studies have provided evidence for multiple additional roles for these signalling proteins in controlling endocytic traffic. Here we review our current understanding of Rho GTPase action within the endocytic pathway and examine the potential points of convergence with the more established, actin-based functions of these signalling proteins.Keywords
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