Progressive supranuclear palsy and tau hyperphosphorylation in a patient with a C212Y parkin mutation

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Abstract
Autosomal recessive-juvenile parkinsonism (AR-JP) is one of the most common forms of familial Parkinson's disease (PD) and is related to mutations in the Park-2 gene, encoding for a protein ligase of ubiquitin, parkin. Different mutations located alo