EFFECT OF FORCED RESTRAINT ON HEART PHOSPHOLIPIDS
Authors:
- P. PrioreschiPPP. Prioreschi
- E. PetermanEPE. Peterman
- 1 May 1967
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 45 (3) , 407-413
Abstract
The cardiac level of phospholipids and their fatty acid composition were measured in the rat after different periods of forced restraint and different periods of rest. After 4 minutes of forced immobilization the level of heart cardiolipin decreased by about 75%. When the animal was immobilized for 24 hours the concentration of cardiolipin in the heart returned to normal after less than 96 hours of rest. The concentration of sphingomyelin was also decreased by forced restraint whereas phosphatidyl ethanolamine decreased only in the resting period after immobilization. The significance of these findings in the pathogenesis of experimental cardiac necroses is discussed.Keywords
This publication has 1 reference indexed in Scilit:
- A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUESJournal of Biological Chemistry, 1957