Neurocognitive Manifestation After Treatment Of Pediatric Severe Anaphylaxis
Authors:
Preprint
- 13 February 2024
- preprint
- Published by Springer Nature in Research Square
Abstract
Background Anaphylaxis is a common yet severe yet life-threatening allergic reaction that occurs rapidly after exposure to an allergen which can affect multiple system in the body. In rare cases, it may lead to additional neurological manifestation that is poorly understood. Case Presentation: We present a case of a 14-year-old boy who experienced severe anaphylaxis necessitating airway intervention and admission to critical care. While his initial presentation and treatment aligned with current standards, he subsequently developed prolonged neurological deficits, including weakness, prosopagnosia, amnesia, and loss of basic functions, during an extended recovery period. Conclusion This rare neurological manifestation following anaphylaxis may be overlooked by many clinicians. Therefore, it is imperative to highlight this potential complication to improve the management of patients experiencing anaphylaxis.Keywords
All Related Versions
- Version 1, 2024-02-13, Research Square
- Published version: BMC Neurology, 25 (1), 1.
This publication has 8 references indexed in Scilit:
- Spinal IL‐33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2‐STAT3 cascadeGlia, 2019
- Diagnosis and management of drug‐induced anaphylaxis in children: An EAACI position paperPediatric Allergy and Immunology, 2019
- Critical Roles of IL-33/ST2 Pathway in Neurological DisordersMediators of Inflammation, 2018
- Outpatient EmergenciesMedical Clinics of North America, 2017
- Elevated serum cytokines during human anaphylaxis: Identification of potential mediators of acute allergic reactionsJournal of Allergy and Clinical Immunology, 2009
- Epinephrine: the drug of choice for anaphylaxis. A statement of the World Allergy OrganizationAllergy, 2008
- Induction of IL-33 expression and activity in central nervous system gliaJournal of Leukocyte Biology, 2008
- Navigating the Updated Anaphylaxis ParametersAllergy, Asthma, and Clinical Immunology, 2007