Quantum Neural Network Classifier for Cancer Registry System Testing: A Feasibility Study
Open Access
- 24 April 2026
- journal article
- Published by Association for Computing Machinery (ACM) in ACM Transactions on Software Engineering and Methodology
- Vol. 35 (5) , 1-24
Abstract
With the rapid advancement of quantum computing, research on quantum machine learning (QML) algorithms has grown significantly. Among these, the Quantum Neural Network (QNN) stands out as one of the promising algorithms that integrates the principles of quantum computing with artificial neural networks to process data. Inspired by applications of QNN across fields, we investigate their use in software testing for the Cancer Registry of Norway (CRN), part of the Norwegian Institute of Public Health (NIPH), responsible for cancer statistics among the Norwegian population. CRN develops a complex socio-technical software system, Cancer Registration Support System ( \(\mathtt{CaReSS}\) ), interacting with many entities (e.g., hospitals, medical laboratories, and other patient registries) to achieve its task. For cost-effective testing of \(\mathtt{CaReSS}\) , CRN has employed \(\mathtt{EvoMaster}\) , an AI-based REST API testing tool combined with an integrated classical machine learning model \(\mathtt{EvoClass}\) . Within this context, we propose \(\mathtt{EvoQlass}\) to investigate the feasibility of using, inside \(\mathtt{EvoMaster}\) , a QNN classifier, instead of the existing classical machine learning model. Results indicate that \(\mathtt{EvoQlass}\) can achieve performance comparable to that of \(\mathtt{EvoClass}\) . We further explore the effects of various QNN configurations on performance and offer recommendations for optimal QNN settings for future QNN developers.
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Funding Information
- Qu-Test project (299827)
- Research Council of Norway and Simula’s internal strategic project on quantum software engineering
- Simula’s internal strategic project on quantum software engineering.
- Oslo Metropolitan University’s
- ASPIRE (JPMJAP2301, JST.)
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