Friedländer reaction of 3‐acetyltropolones: Synthesis of naphthyridinyl‐ and allied heterocyclic‐substituted tropolones
Authors:
- 1 March 1996
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 33 (2) , 389-398
Abstract
Five 3‐acetyltropolones reacted with 2‐amino‐3‐pyridinecarbaldehyde to afford the corresponding 3‐(1,8‐naphthyridin‐2‐yl)tropolones in excellent yields. In a similar manner, 1,6‐naphthyridin‐2‐yl‐,1,7‐naphthyridin‐2‐yl‐, 6‐pyrido[2,3‐b]pyrazinyl‐, and 1‐methyl‐6‐pyrazolo[5,4‐b]pyridyl‐substituted tropolones were prepared. Reactivities of amino‐substituted heteroarenecarbaldehydes in these reactions and properties of the products are also discussed.Keywords
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