Possible carriers in erythrocytes

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Abstract
Using a densimeter technique, the effect of tannic acid and n‐butanol on the permeability to non‐electrolytes of erythrocytes of various species was studied. If both tannic acid and butanol decrease the permeability it is suggested that a carrier mechanism is involved. If tannic acid has little or no effect and butanol increases the permeability it is suggested that the penetration of such a molecule depends only on diffusion. According to this theory carriers are involved in the following systems: Urea — mouse, sheep, pig, ox and man; Ethylene glycol — man and possibly mouse; Glycerol — man, mouse, rabbit; Erythritol — mouse and possibly man; Ribose — mouse, man; Mannose, glucose, sorbose — man. No carriors are involved in the following systems: Urea — chicken; Ethylene glycol — pig, chicken, ox, sheep; Thiourea — rabbit, chicken, sheep, man, pig, ox; Glycerol — chicken, pig, sheep, ox; Erythritol — rabbit; Ribose — rabbit.

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