The Effects of Chloroquine on Serum 1,25-Dihydroxyvitamin D and Calcium Metabolism in Sarcoidosis

Authors:
  • TOTimothy J. O'Leary
    Timothy J. O'Leary
  • GJGlenville Jones
    Glenville Jones
  • AYAgatha Yip
    Agatha Yip
  • DLDavid Lohnes
    David Lohnes
  • MCMoussa Cohanim
    Moussa Cohanim
  • EYEdmund R. Yendt
    Edmund R. Yendt

Abstract
Although corticosteroids are effective in the treatment of hypercalciuria and hypercalcemia in chronic sarcoidosis, complications of their long-term use frequently limit therapy. We studied the efficacy of chloroquine in two patients with sarcoidosis who were unable to tolerate the dosage of corticosteroids required to control hypercalciuria and prevent the formation of renal stones.

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