Lichen planus flare following COVID‐19 vaccination: A case report
Authors:
Open Access
- 7 December 2021
- journal article
- case report
- Published by Wiley in Clinical Case Reports
- Vol. 9 (12) , e05092
Abstract
We report the third case of cutaneous lichen planus (LP) following COVID‐19 BNT162b2 vaccination in a 59‐year‐old woman with previous LP. The reactivation of LP in patients with dormant LP suggests a possible vaccine‐induced immune dysregulation. We suggest that the already described vaccine‐induced upregulation of Th1 response may play a relevant role in LP reactivation, through an increase in inflammatory cytokines involved in the pathogenesis of LP. Interestingly, LP has already been associated with vaccinations and viral infections including COVID‐19 disease. However, the exact mechanism underlying LP (re)activation after Pfizer‐BiotNtech COVID‐19 vaccination is still widely unknown and needs to be further investigated.Keywords
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This publication has 10 references indexed in Scilit:
- Development of oral lichen planus after COVID‐19 vaccination – a rare case reportJournal of the European Academy of Dermatology and Venereology, 2021
- Lichenoid cutaneous skin eruption and associated systemic inflammatory response following Pfizer‐BioNTech mRNA COVID‐19 vaccine administrationRespirology Case Reports, 2021
- New‐onset cutaneous lichen planus triggered by COVID‐19 vaccinationJournal of the European Academy of Dermatology and Venereology, 2021
- Oxidative Stress in Cutaneous Lichen Planus—A Narrative ReviewJournal of Clinical Medicine, 2021
- Lack of Informations about COVID-19 Vaccine: From Implications to Intervention for Supporting Public Health Communications in COVID-19 PandemicInternational Journal of Environmental Research and Public Health, 2021
- Lichen planus arising after COVID‐19 vaccinationJournal of the European Academy of Dermatology and Venereology, 2021
- Publisher Correction: COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responsesNature, 2021
- Acute urticarial rash after COVID-19 vaccination containing Polysorbate 80Clinical and Experimental Vaccine Research, 2021
- Coronavirus disease (COVID‐19): An updated review based on current knowledge and existing literature for dermatologistsDermatologic Therapy, 2020
- Lichen planus as a Side Effect of HBV VaccinationDermatology, 1999