Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity
- 28 October 2020
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Translational Medicine
- Vol. 12 (567)
Abstract
Mohawk is enriched in meniscal tissue and promotes meniscus cell phenotype, enhances repair, and protects against cartilage destruction in mice.Keywords
Funding Information
- National Institutes of Health (AG007996)
- National Institutes of Health (AR065379)
This publication has 54 references indexed in Scilit:
- The Genotype-Tissue Expression (GTEx) projectNature Genetics, 2013
- STAR: ultrafast universal RNA-seq alignerBioinformatics, 2012
- The knee meniscus: Structure–function, pathophysiology, current repair techniques, and prospects for regenerationBiomaterials, 2011
- Macroscopic and histopathologic analysis of human knee menisci in aging and osteoarthritisOsteoarthritis and Cartilage, 2011
- EGR1 and EGR2 Involvement in Vertebrate Tendon DifferentiationJournal of Biological Chemistry, 2011
- CTGF directs fibroblast differentiation from human mesenchymal stem/stromal cells and defines connective tissue healing in a rodent injury modelJournal of Clinical Investigation, 2010
- Hypertrophy in Mesenchymal Stem Cell Chondrogenesis: Effect of TGF-β Isoforms and Chondrogenic ConditioningCells Tissues Organs, 2010
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression dataBioinformatics, 2009
- Chondrogenesis of Adult Stem Cells from Adipose Tissue and Bone Marrow: Induction by Growth Factors and Cartilage-Derived MatrixTissue Engineering Part A, 2009
- Smad-Independent Transforming Growth Factor-β Regulation of Early Growth Response-1 and Sustained Expression in FibrosisThe American Journal of Pathology, 2008