Biocatalytic Synthesis of Chiral Polyoxygenated Compounds: Effect of the Solvent on the Enantioselectivity of Lipase Catalyzed Transesterifications in Organic Solvents

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  • BHBernardo Herradón
    Bernardo Herradón
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Abstract
The influence of the solvent on the transesterification between vinyl acetate and cis-(±)-4-hydroxymethyl-2-phenyl-1,3-dioxane [(±)--1] catalyzed by Pseudomonas fluorescens lipase has been studied. It was found that the enantioselectivity of the process depends on both the hydrophobicity and the polarity of the solvent.