Aberration correction in holographic optical tweezers using a high-order optical vortex

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Abstract
Holographic optical tweezers are a powerful optical trapping and manipulation tool in numerous applications such as life science and colloidal physics. However, imperfections in the spatial light modulator and optical components of the system will introduce detrimental aberrations to the system, thereby degrading the trapping performance significantly. To address this issue, we develop an aberration correction technique by using a high-order vortex as the correction metric. The optimal Zernike polynomial coefficients for quantifying the system aberrations are determined by comparing the distorted vortex and the ideal one. Efficiency of the proposed method is demonstrated by comparing the optical trap intensity distribution, trap stiffness, and particle dynamics in a Gaussian trap and an optical vortex trap, before and after aberration corrections.
Funding Information
  • National Key Research, Development Program of China (2017YFC0110100)
  • National Natural Science Foundation of China (NSFC) (61522511, 81427802, 11474352)
  • National Institutes of Health (NIH) (GM100156)

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