GreenSound-PNA toward a more sustainable ultrasound-assisted solid phase synthesis of peptide nucleic acids
- 12 October 2026
- journal article
- Published by Royal Society of Chemistry (RSC) in Green Chemistry
- Vol. 28 (39) , 15699-15718
Abstract
GreenSound-PNAs combines ultrasound-assisted PNA synthesis with greener solvents and reagents, enabling a more sustainable, scalable, and efficient platform for PNA production.Keywords
Funding Information
- Ministero dell'Università e della Ricerca (2022CFP37H_003)
- Ministero dell'Università e della Ricerca (P20225ZAMB_02)
- Ministero dell'Università e della Ricerca (P2022KCW3L_003)
This publication has 115 references indexed in Scilit:
- Addressing Sustainability Challenges in Peptide Synthesis with Flow Chemistry and Machine LearningChemistry – A European Journal, 2025
- Scope and Limitations of the Use of Methanesulfonic Acid (MSA) as a Green Acid for Global Deprotection in Solid‐Phase Peptide SynthesisChemSusChem, 2025
- Peptide Nucleic Acids: From Origami to EditingChempluschem, 2024
- Circular Aqueous Fmoc/t‐Bu Solid‐Phase Peptide SynthesisChemSusChem, 2021
- Optimized Synthesis of Fmoc/Boc‐Protected PNA Monomers and their Assembly into PNA Oligomers.European Journal of Organic Chemistry, 2021
- N‐Butylpyrrolidinone for Solid‐Phase Peptide Synthesis is Environmentally Friendlier and Synthetically Better than DMFChemSusChem, 2020
- Disulfide Bond Replacement with 1,4‐ and 1,5‐Disubstituted [1,2,3]‐Triazole on C‐X‐C Chemokine Receptor Type 4 (CXCR4) Peptide Ligands: Small Changes that Make Big DifferencesChemistry – A European Journal, 2020
- Sustainable Peptide Synthesis Enabled by a Transient Protecting GroupAngewandte Chemie International Edition, 2020
- Expanding the Scope of PNA‐Encoded Synthesis (PES): Mtt‐Protected PNA Fully Orthogonal to Fmoc Chemistry and a Broad Array of Robust Diversity‐Generating ReactionsChemistry – A European Journal, 2012
- Applied Sonochemistry2002