Synthesis of antigenic carbohydrate polymers recognized by lectins and antibodies

Authors:
  • RRRené Roy
    René Roy
  • FTFrançois D. Tropper
    François D. Tropper
Publisher website
Google Scholar
Abstract
The alkene group of allyl α-L-rhamnopyranoside has been converted to an N-acryloyl spacer arm which was copolymerized with acrylamide to afford water soluble carbohydrate copolymers; these have antigenic properties demonstrated by their binding to Ricinus communis lectin and to the antisera to the capsular polysaccharide of Streptococcus pneumoniae type 23.