Detection of viral hepatitis type A.

Authors:
  • FHF B Hollinger
    F B Hollinger
  • DBD W Bradley
    D W Bradley
  • GDG R Dreesman
    G R Dreesman
  • JMJ L Melnick
    J L Melnick

  • 1 May 1976
    • journal article
Abstract
Several technics are currently being used to detect hepatitis type A antigen or its antibody. These include immunoelectronmicroscopy, immune adherence, and complement fixation. This paper describes another promising technic, a microtiter solid-phase immunoradiometric assay, in which hepatitis A antigen and antibody are detected. Such a method can be utilized for biochemical and biophysical analysis of purified particles, for the seroepidemiology of type A hepatitis, and as a means for monitoring hepatitis A antigen in cell cultures.