Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay
Authors:
- Hiroshi YamazakiHYHiroshi Yamazaki
- Yoshimitsu OdaYOYoshimitsu Oda
- F.PEter GuengerichFGF.PEter Guengerich
- Miki NakajimaMNMiki Nakajima
- Tsuyoshi YokoiTYTsuyoshi Yokoi
- 1 October 2001
- journal article
- Published by Elsevier in Mutation Research - Genetic Toxicology and Environmental Mutagenesis
- Vol. 497 (1-2) , 223-233
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Health
- Ministry of Education, Culture, Sports, Science and Technology
This publication has 38 references indexed in Scilit:
- P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclaturePharmacogenetics, 1996
- Distribution of nitropyrenes and mutagenicity in airborne particulates collected with an Andersen samplerMutation Research Letters, 1995
- Assessment of occupational exposure to diesel exhaust. The use of an immunoassay for the determination of urinary metabolites of nitroarenes and polycyclic aromatic hydrocarbonsToxicology Letters, 1994
- Determination of 1,3-, 1,6-, 1,8-Dinitropyrenes and 1-Nitropyrene in Vehicle Exhaust Particulates.Eisei kagaku, 1994
- A sensitive umu test system for the detection of mutagenic nitroarenes in Salmonella typhimurium NM1011 having a high nitroreductase activityMutation Research/Environmental Mutagenesis and Related Subjects, 1992
- N- and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cellsBiochemical and Biophysical Research Communications, 1992
- Synthesis and mutagenicity of 1-nitropyrene 4,5-oxide and 1-nitro-pyrene 9,10-oxide, microsomal metabolites of 1-nitropyreneMutagenesis, 1986
- Aerobic and anaerobic reduction of nitrated pyrenes in vitroChemico-Biological Interactions, 1986
- Metabolism of chemical carcinogensPharmacology & Therapeutics, 1985
- Excretion and metabolism of 1-nitropyrene in rats after oral or intraperitoneal administration*1Fundamental and Applied Toxicology, 1985