Enhanced visualization and quantification of magnetic resonance diffusion tensor imaging using thep:qtensor decomposition
Authors:
- H A L GreenHGH A L Green
- T A CarpenterTCT A Carpenter
- S J PriceSPS J Price
- J D PickardJPJ D Pickard
- J H GillardJGJ H Gillard
- 1 February 2006
- journal article
- Published by Oxford University Press (OUP) in British Journal of Radiology
- Vol. 79 (938) , 101-109
Abstract
Many scalar measures have been proposed to quantify magnetic resonance diffusion tensor imaging (MR DTI) data in the brain. However, only two parameters are commonly used in the literature: mean diffusion (D) and fractional anisotropy (FA). We introduce a visualization technique which permits the simultaneous analysis of an additional five scalar measures. This enhanced diversity is important, as it is not known a priori which of these measures best describes pathological changes for brain tissue. The proposed technique is based on a tensor transformation, which decomposes the diffusion tensor into its isotropic (p) and anisotropic (q) components. To illustrate the use of this technique, diffusion tensor imaging was performed on a healthy volunteer, a sequential study in a patient with recent stroke, a patient with hydrocephalus and a patient with an intracranial tumour. Our results demonstrate a clear distinction between different anatomical regions in the normal volunteer and the evolution of the pathol...Keywords
This publication has 36 references indexed in Scilit:
- A diffusion tensor magnetic resonance imaging study of brain tissue from patients with migraineJournal of Neurology, Neurosurgery & Psychiatry, 2003
- Monitoring Disease Progression in CADASIL With Diffusion Magnetic Resonance ImagingStroke, 2002
- Increased Anisotropy in Acute StrokeStroke, 2002
- Diffusion tensor imaging of cryptogenic and acquired partial epilepsiesBrain, 2001
- Diffusion tensor imaging demonstrates deviation of fibres in normal appearing white matter adjacent to a brain tumourJournal of Neurology, Neurosurgery & Psychiatry, 2000
- Neuropathological abnormalities of the corpus callosum in schizophrenia: a diffusion tensor imaging studyJournal of Neurology, Neurosurgery & Psychiatry, 2000
- Invariant and Orthonormal Scalar Measures Derived from Magnetic Resonance Diffusion Tensor ImagingJournal of Magnetic Resonance, 1999
- A Comparative Study of Acquisition Schemes for Diffusion Tensor Imaging Using MRIJournal of Magnetic Resonance, 1999
- Toward a quantitative assessment of diffusion anisotropyMagnetic Resonance in Medicine, 1996
- Inferring microstructural features and the physiological state of tissues from diffusion‐weighted imagesNMR in Biomedicine, 1995