Septic shock in older people: a prospective cohort study
Authors:
- Fabiano Pinheiro da SilvaFSFabiano Pinheiro da Silva
- Fernando Godinho ZampieriFZFernando Godinho Zampieri
- Denise Frediani BarbeiroDBDenise Frediani Barbeiro
- Hermes Vieira BarbeiroHBHermes Vieira Barbeiro
- Alessandra Carvalho GoulartAGAlessandra Carvalho Goulart
- Francisco Torggler FilhoFFFrancisco Torggler Filho
- Irineu Tadeu VelascoIVIrineu Tadeu Velasco
- Luiz Monteiro da Cruz NetoLNLuiz Monteiro da Cruz Neto
- Heraldo Possolo de SouzaHSHeraldo Possolo de Souza
- Marcel Cerqueira César MachadoMMMarcel Cerqueira César Machado
Open Access
- 6 June 2013
- journal article
- research article
- Published by Springer Nature in Immunity & Ageing
- Vol. 10 (1) , 21
Abstract
Septic shock is the first cause of death in Intensive Care Units. Despite experimental data showing increased inflammatory response of aged animals following infection, the current accepted hypothesis claims that aged patients are immunocompromised, when compared to young individuals. Here, we describe a prospective cohort study designed to analyze the immune profile of this population. Older people are as immunocompetent as the young individual, regarding the cytokines, chemokines and growth factors response to devastating infection.Keywords
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