Immunostimulating hexapeptide from human casein: amino acid sequence, synthesis and biological properties
Authors:
Open Access
- 1 December 1984
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 145 (3) , 677-682
Abstract
A hexapeptide obtained from human casein by enzymatic digestion has been purified, sequenced and synthesized; its structure is: Val‐Glu‐Pro‐Ile‐Pro‐Tyr. In vitro this hexapeptide stimulates the phagocytosis of opsonized sheep red blood cells by murine peritoneal macrophages. Administered intravenously to adult mice, it enhances the resistance to infection with Klebsiella pneumoniae.Keywords
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