Detectability of damage using Lamb waves depends on many factors such as size and severity of damage, attenuation of the wave and distance to the transducers. This paper presents a detectability model for pitch-catch sensors configuration for structural health monitoring (SHM) applications. The proposed model considers the physical properties of lamb wave propagation and is independent of damage detection algorithm, which provides a generic solution for probability of detection. The applicability of the model in different environmental and operational conditions is also discussed.