Visible‐Light‐Mediated Photocatalytic Difunctionalization of Olefins by Radical Acylarylation and Tandem Acylation/Semipinacol Rearrangement
- 19 January 2016
- journal article
- research article
- Published by Wiley in Chemistry – A European Journal
- Vol. 22 (10) , 3292-3295
Abstract
A novel method for the mild photoredox‐mediated tandem radical acylarylation and tandem acylation/semipinacol rearrangement has been developed. The synthesis of highly functionalized ketones bearing all‐carbon α‐ or β‐quaternary centers has been achieved using easily available symmetric aromatic carboxylic anhydrides as the acyl radical source. The method allows for a straightforward introduction of the keto functionality and concomitant construction of molecular complexity in a single operation.Keywords
Funding Information
- Olle Engkvist Byggmästare foundation
- Wilhelm and Martina Lundgren research foundation
- Ollie and Elof foundation
- Magnus Bergvall Foundation
- Adlerbertska Foundation
- Swedish Research Council
- European Commission (660668)
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