Diastereo- and enantioselective construction of cyclohexanone-fused spirospyrazolones containing four consecutive stereocenters through asymmetric sequential reactions
Authors:
- 29 June 2016
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic Chemistry Frontiers
- Vol. 3 (9) , 1087-1090
Abstract
The diastereo- and enantioselective synthesis of cyclohexanone-fused spirospyrazolones through an asymmetric Michael/Michael/aldol cascade reaction catalyzed by squaramide and diphenylprolinol silyl ether, followed by a sequential oxidation was developed.Keywords
Funding Information
- National Natural Science Foundation of China (21272024)
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