Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ
- 1 December 2013
- journal article
- research article
- Published by Springer Nature in Nature Structural & Molecular Biology
- Vol. 21 (1) , 49-55
Abstract
The first X-ray crystal structure of the catalytic core of Saccharomyces cerevisiae DNA polymerase ɛ with a primed DNA template and an incoming dNTP reveals a new 'P domain' that encircles the DNA and contributes to the high processivity of this replicative polymerase.Keywords
This publication has 54 references indexed in Scilit:
- Integrated genomic characterization of endometrial carcinomaNature, 2013
- Mechanism for priming DNA synthesis by yeast DNA Polymerase αeLife, 2013
- Watching DNA polymerase η make a phosphodiester bondNature, 2012
- Probing Minor Groove Hydrogen Bonding Interactions between RB69 DNA Polymerase and DNABiochemistry, 2012
- Insights into Base Selectivity from the 1.8 Å Resolution Structure of an RB69 DNA Polymerase Ternary ComplexBiochemistry, 2010
- Structural diversity of the Y-family DNA polymerasesBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2010
- Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δNature Structural & Molecular Biology, 2009
- Division of Labor at the Eukaryotic Replication ForkMolecular Cell, 2008
- Role of the catalytic metal during polymerization by DNA polymerase lambdaDNA Repair, 2007
- Structure of the Replicating Complex of a Pol α Family DNA PolymeraseCell, 2001