When are laboratory tests indicated in patients with vitiligo?
Open Access
- 1 January 2012
- journal article
- Published by Taylor & Francis in Dermato-Endocrinology
- Vol. 4 (1) , 53-57
Abstract
Background: Vitiligo has been associated with multiple endocrine and immune conditions. Several laboratory tests have been assessed in this disease with controversial results. Objective: The aim of this study is to analyze the levels autoantibodies, basal glycaemia, vitamin B12, folic acid and thyroid function and its association with the diagnosis and outcome of vitiligo patients through a case-control study. Material and methods: This case-control study was performed on 196 consecutive patients with vitiligo referred to our Dermatology Department. As a control group, 160 healthy individuals without vitiligo or known history of immunologic/endocrine disease were included. Data were analyzed using the SPSS 17.0 statistical software package. Results: Clinical, analytical and demographic data have been recorded. Our results showed that anti-thyroid peroxidase antibody and anti-parietal gastric cell antibody could be useful laboratory markers in a subpopulation of vitiligo patients. However, testing anti-nuc...Keywords
This publication has 14 references indexed in Scilit:
- Serum homocysteine, folic acid and vitamin B12 levels in vitiligoEuropean Journal Of Dermatology, 2009
- Randomized, double-blind clinical trial to evaluate the efficacy of topical tacalcitol and sunlight exposure in the treatment of adult nonsegmental vitiligoBritish Journal of Dermatology, 2009
- Guideline for the diagnosis and management of vitiligoBritish Journal of Dermatology, 2008
- The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task ForcePigment Cell Research, 2007
- The genetics of generalized vitiligo and associated autoimmune diseasesJournal of Dermatological Science, 2006
- A Critical Appraisal of Vitiligo Etiologic Theories. Is Melanocyte Loss a Melanocytorrhagy?Pigment Cell Research, 2003
- Immunoprecipitation of melanogenic enzyme autoantigens with vitiligo sera: evidence for cross-reactive autoantibodies to tyrosinase and tyrosinase-related protein-2 (TRP-2)Clinical and Experimental Immunology, 1997
- Cytolytic Antibodies to Melanocytes in VitiligoJournal of Investigative Dermatology, 1993
- Relation Between the Incidence and Level of Pigment Cell Antibodies and Disease Activity in VitiligoJournal of Investigative Dermatology, 1991
- Clinical features and course of type A and type B vitiligoBritish Journal of Dermatology, 1988