Glaucoma-associated polymorphism M98K-OPTN sensitizes retinal cells to protein homeostasis stress through p62-mediated caspase activation
- 25 September 2025
- journal article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Vol. 1873 (1) , 120064
Abstract
No abstract availableKeywords
Funding Information
- Indian National Science Academy
- Department of Science and Technology (DST/WOS-A/LS-261/2019)
This publication has 66 references indexed in Scilit:
- Molecular aspects of cytoprotection by Optineurin during stress and diseaseBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2025
- Optineurin modulates ER stress-induced signaling pathways and cell deathBiochemical and Biophysical Research Communications, 2021
- Major review: Molecular genetics of primary open-angle glaucomaExperimental Eye Research, 2017
- Targeting the ubiquitin proteasome system in haematological malignanciesBlood Reviews, 2013
- Oxidative stress and mitochondrial dysfunction in glaucomaCurrent Opinion in Pharmacology, 2013
- Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis SignalingCell, 2009
- Oxidative and nitrative stress markers in glaucomaFree Radical Biology and Medicine, 2008
- Optineurin Negatively Regulates TNFα- Induced NF-κB Activation by Competing with NEMO for Ubiquitinated RIPCurrent Biology, 2007
- Age-dependent inhibition of proteasome chymotrypsin-like activity in the retinaExperimental Eye Research, 2007
- Proteasome Function and Protein Oxidation in the Aged RetinaExperimental Eye Research, 2002