An Improved Three Step Synthesis of (-)-3β-Hydroxycarvone from (-)-Carvone
Open Access
- 28 February 2002
- Vol. 7 (2) , 129-134
Abstract
(-)-Carvone (3) has been efficiently transformed into (-)-3β-hydroxycarvone (1), which is expected to be a useful synthon or chiral template in the synthesis of natural molecules. This short and efficient synthesis of compound 1 involves regioselective and stereoselective α-hydroxylation of carvone via the trimethylsilyl-dienyl-ether derivative.Keywords
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