Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators

This publication has 72 references indexed in Scilit:

• Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts
  Free Radical Biology and Medicine, 2011
• Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin
  Toxicology Letters, 2011
• 2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin
  Toxicology, 2011
• Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
  Toxicology and Applied Pharmacology, 2010
• Biological and Molecular Mechanisms of Sulfur Mustard Analogue-Induced Toxicity in JB6 and HaCaT Cells: Possible Role of Ataxia Telangiectasia-Mutated/Ataxia Telangiectasia-Rad3-Related Cell Cycle Checkpoint Pathway
  Chemical Research in Toxicology, 2010
• Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide
  Toxicology and Applied Pharmacology, 2010
• Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice
  Free Radical Biology and Medicine, 2009
• Free radical production from the interaction of 2-chloroethyl vesicants (mustard gas) with pyridine nucleotide-driven flavoprotein electron transport systems
  Toxicology and Applied Pharmacology, 2009
• Matrix metalloproteinases as modulators of inflammation and innate immunity
  Nature Reviews Immunology, 2004
• Signal transduction events in lung injury induced by 2‐chloroethyl ethyl sulfide, a mustard analog
  Journal of Biochemical and Molecular Toxicology, 2003