The competitive equilibrium between aluminium and ferric ions for the binding sites of transferrin
Authors:
- 15 October 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 176 (1) , 129-132
Abstract
Human transferrin is shown to bind 2 mol of aluminium per mol of protein using spectrophotometric titration. Competitive equilibrium between aluminium and ferric ions for transferrin binding sites is observed, and a value of 2.5 (± 0.4) × 1015 M−1 is found for the apparent binding constant under physiological conditions.Keywords
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