Steely Hair, Mottled Mice and Copper Metabolism

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  • DDDavid M. Danks
    David M. Danks
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Abstract
Copper, an extremely important trace element in animal and human metabolism,1 2 3 is necessary for the normal function of many enzymes. The effects of nutritional deficiency have been studied in sheep, rats, mice, pigs, chickens and turkeys and include changes in integument, bone, arteries, pigmentation and brain.1 2 3 Copper deficiency in human infants has been studied extensively in Peru4 and has recently been reported in a few babies fed on synthetic diets,5 , 6 or nourished intravenously.7 The disturbance of nutrition has always been complex, and assignment of particular effects to copper deficiency has depended upon serial replacement of other nutrients — a rather . . .
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