Geriatric sarcopenia is associated with hypertension: A systematic review and meta‐analysis
Open Access
- 18 August 2023
- journal article
- review article
- Published by Wiley in The Journal of Clinical Hypertension
- Vol. 25 (9) , 808-816
Abstract
This meta‐analysis aimed to explore the potential relationship between senile sarcopenia and hypertension in older people. A comprehensive search was conducted in PubMed, Embase, Web of Science, and the Cochrane Library, up to November 2022. Ten studies comprising 14 804 participants were enrolled. The odds ratio (OR) and 95% confidence interval (CI) was pooled to evaluate the correlation between sarcopenia and hypertension in older people utilizing a random‐effects model. Subgroup and sensitivity analyses were then carried out to explore the potential sources of heterogeneity. The results revealed a substantial correlation between sarcopenia and hypertension among older people (OR = 1.39, 95% CI: 1.15–1.67, p < .01). Further subgroup analysis revealed an association between sarcopenic obesity and hypertension (OR = 1.49, 95% CI: 1.37–1.62, p < .01). In conclusions, our findings highlighted a significant relationship between sarcopenia and hypertension among older people, with sarcopenic obesity amplifying this risk.Keywords
This publication has 37 references indexed in Scilit:
- Sarcopenic obesity or obese sarcopenia: A cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the pathogenesisAgeing Research Reviews, 2017
- Serum markers of inflammation and oxidative stress in sarcopeniaAging Clinical and Experimental Research, 2016
- Prevalence of sarcopenia in older Brazilians: A systematic review and meta‐analysisGeriatrics & Gerontology International, 2016
- Sarcopenia Is Associated with High Pulse Pressure in Older WomenJournal of Aging Research, 2015
- Incidence and Predictors of Sarcopenia Onset in Community-Dwelling Elderly Japanese Women: 4-Year Follow-Up StudyJournal of the American Medical Directors Association, 2015
- Sarcopenia as a Determinant of Blood Pressure in Older Koreans: Findings from the Korea National Health and Nutrition Examination Surveys (KNHANES) 2008–2010PLOS ONE, 2014
- Sarcopenia Is Independently Associated with Cardiovascular Disease in Older Korean Adults: The Korea National Health and Nutrition Examination Survey (KNHANES) from 2009PLOS ONE, 2013
- Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE studyAge and Ageing, 2013
- Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 DiabetesDiabetes Care, 2010
- Sarcopenia: European consensus on definition and diagnosisAge and Ageing, 2010