C4-P-05Fusion of plasma membrane between NG2-Expressing Progenitor Cells and Neurons in the Cerebral Cortex of Rats

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Abstract
NG2-expressing progenitor cells (NG2 cells) [ 1 , 2 ] are often located adjacent to neuronal somata in the central nervous system [ 3 ]. We have evaluated the microstructure of their cell adhesion by comparing that with other glial cells, using a transmission electron microscope (TEM) and a scanning electron microscopes (SEM) as well as an optical microscope. Following the identification of structural feature of NG2 cells by immuno-electron microscope, the adhesion manner of glial cells including NG2 cells and neurons was observed using a TEM. The TEM image indicated that many NG2 progenitor cells cut deep into the cytoplasm of neurons. Furthermore, the 3D reconstruction of microstructure of the cell adhesion manner using a SEM revealed a partial disappearance of plasma membrane separating...