Transposable elements and the dynamic somatic genome
Authors:
Open Access
- 1 January 2007
- journal article
- review article
- Published by Springer Nature in Genome Biology
- Vol. 8 (Suppl 1) , S5
Abstract
Although alterations in the genomes of somatic cells cannot be passed on to future generations, they can have beneficial or detrimental effects on the host organism, depending on the context in which they occur. This review outlines the ways in which transposable elements have important consequences for somatic cell genomes.Keywords
This publication has 55 references indexed in Scilit:
- The Human SETMAR Protein Preserves Most of the Activities of the Ancestral Hsmar1 TransposaseMolecular and Cellular Biology, 2007
- Turning junk into gold: domestication of transposable elements and the creation of new genes in eukaryotesBioEssays, 2006
- Birth of a chimeric primate gene by capture of the transposase gene from a mobile elementProceedings of the National Academy of Sciences, 2006
- From the margins of the genome: mobile elements shape primate evolutionBioEssays, 2005
- LINE-1 retrotransposons: Modulators of quantity and quality of mammalian gene expression?BioEssays, 2005
- A systematic analysis of LINE-1 endonuclease-dependent retrotranspositional events causing human genetic diseaseHuman Genetics, 2005
- Mobile Elements: Drivers of Genome EvolutionScience, 2004
- SVA Elements Are Nonautonomous Retrotransposons that Cause Disease in HumansThe American Journal of Human Genetics, 2003
- Alu repeats and human genomic diversityNature Reviews Genetics, 2002
- P-element homologous sequences are tandemly repeated in the genome of Drosophila guanche.Proceedings of the National Academy of Sciences, 1992